Fig. 5.

Positional variance diagram of the central ordering. The x-axis is the event position. The top panel shows the population-level positional variance diagram of the central ordering for the female APOE ɛ4 carriers. The bottom panel shows the subject-level positional variance diagram of the central ordering for the APOE ɛ4 carriers. Abbreviations: PET, positron emission tomography; CSF, cerebrospinal fluid; p-tau, phosphorylated tau; Aβ, amyloid-β; RAVLT, Rey Auditory Visual Learning Test; MidTemp, middle temporal gyrus; FDG, fluorodeoxyglucose; ADAS13, Alzheimer's Disease Assessment Scale (13-item version); MMSE, Mini–Mental State Examination; CDRSB, Clinical Dementia Rating Scale Sum of Boxes; FAQ, Functional Activities Questionnaire; APOE ɛ4, apolipoprotein E ε4.