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. 2018 Oct 25;11(5):1075–1091. doi: 10.1016/j.stemcr.2018.10.001

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© 2018 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Important Frequency and LTC-IC Defect in the CD34⁺CD38⁻CD45⁺CD117^hi HSC-Enriched Population of a Human FA 13 WG FL

(A) Comparison of the frequency of CD34⁺CD38⁻CD45⁺CD117^hi HSC-enriched population from an FA (FANCB) FL or from an age-matched control FL (13 WG).

(B) Comparison of LTC-IC frequency of CD34⁺CD38⁻CD45⁺CD117^hi cells sorted from an FA (FANCB) FL (13 WG) and from two age-matched control FL (13 and 17.7 WG).

Error bars correspond to standard deviation. Black bar, control FL; white bar, FA FL.