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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Environ Int. 2018 Jan 8;111:260–267. doi: 10.1016/j.envint.2017.12.019

Fig. 2.

Fig. 2.

Simulated plasma PFOA concentrations in CD-1 dam/pups and human mother/child. For the CD-1 dam and pups, lines represent simulated PFOA levels for a maternal PFOA dose of 1 mg/kg/day for gestational days 1–17(litter size of 10). Mean (•) and standard deviation (error bars) of serum PFOA levels in pups from the Macon et al. (2011) study are also presented. For the human mother and child, lines represent simulated PFOA levels for a maternal daily intake (3.2 × 10−4 mg/kg/d) leading to an average overall concentration in the child matching that from the simulation for CD-1 pups. Age 0 in both graphs indicates delivery. Dashed lines represent plasma PFOA concentrations in the dam/mother, thick solid line represents plasma PFOA concentrations in the pup/child. Simulations for humans start at maternal age 0, but only the four years prior to delivery are presented in the figure.