Table 1.

Olanzapine-induced blood dyscrasias in the elderly

Author/year	Patient details	Dose of olanzapine	Detected after days of initiation of olanzapine	Treatment/outcome
Meissner et al, 27 1999	56-year-old woman with parkinsonism 58-year-old man with parkinsonism	15 mg 5 mg	120 days 156 days	Reversibility of leucopaenia after stoppage of olanzapine
Steinwachs et al, 23 1999	81-year-old woman with schizophrenia	10 mg	17 days	Reversibility of neutropaenia after stoppage of olanzapine
Teter et al, 29 2000	60-year-old man with psychosis	20 mg	204 days	Patient had a history of treatment with clozapine and developed neutropaenia subsequent to use of olanzapine which improved after stoppage of the drug
Onofrj and Thomas,14 2001	67-year-old man with Parkinson’s disease and psychosis	10 mg	35 days	Stoppage of olanzapine improved pancytopaenia and thrombocytopaenia in 14 days
Carrillo et al, 15 2004	78-year-old man with dementia	10 mg	21 days	Death
Mehta and Sanitato,13 2005	83-year-old woman with dementia and depression	2.5 mg	1 day	Stoppage of olanzapine plus treated with G-CSF led to improvement
Stergiou et al, 28 2005	69-year-old woman with psychosis	10 mg	17 days	Stoppage of drug

G-CSF, granulocyte colony stimulating factor.