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. 2018 Nov 8;5:99–108. doi: 10.2147/JHC.S159808

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© 2018 Quaglia. This work is published and licensed by Dove Medical Press Limited

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Inflammatory hepatocellular adenoma with focal signs of concomitant beta-catenin activation.

Notes: (A) H&E section showed an area of increased cell density (asterisks) in comparison to a nearby one in which hepatocytes are more of normal size (arrows). (B) Beta-catenin immunostain from the same area shows nuclear staining in places (arrows). (C) Glutamine synthetase is diffusely expressed in this area. (D) Serum amyloid A is expressed by nearby hepatocytes (arrows). Courtesy Dr Andrew Drake, Christchurch, New Zealand.