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. 2018 Nov 9;6(1):e000560. doi: 10.1136/bmjdrc-2018-000560

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© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Estimated glucose delta values (mmol/L) after glucagon injection (5 µg/kg) in octreotide-treated rats. Green line represents intravenous (IV) intervention, blue line represents subcutaneous (SC) intervention, and red line represents intraperitoneal (IP) intervention. The glucose response for the placebo group has been subtracted from all groups presented in the figure. *Represents significant difference between intraperitoneal and subcutaneous of glucagon delivery. Note: For one rat in intraperitoneal intervention, delta values were calculated using the −5 minute measurement (−1 minute for other rats).