Fig. 4.

Role of TRRAP on in vivo tumor growth of A2780 sphere cells. (A) Effects of TRRAP knockdown on the in vivo growth of xenograft transplanted A2780-SP cells. A2780-SP cells were infected with lentiviruses expressing sh-control or sh-TRRAP and then transplanted into nude mice. Representative images are shown of xenograft tumors 38 days after transplanting A2780-SP cells infected with sh-control or sh-TRRAP lentiviruses. (B) Tumor volumes were measured daily from days 14 to 38 after injecting A2780-SP cells. (C) Tumor weights were measured 38 days after transplanting A2780-SP cells. Results are presented as mean ± SD. *P < 0.05 (n = 8).