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. Author manuscript; available in PMC: 2018 Nov 14.
Published in final edited form as: Cancer Res. 2018 May 2;78(13):3672–3687. doi: 10.1158/0008-5472.CAN-17-3167

Figure 6: Responses in ERK signaling following MET and MEK inhibition in NF1 MPNST Models.

Figure 6:

(A) Immunostaining of pERK (T202/Y204) in MPNST models that were treated with kinase inhibitors for 2 days (areas of strongest signal are shown in the magnified inset boxes). (B-D) Western Blot analysis of MPNST cells treated with TKIs for 2 hours and +/− HGF for pERK (left panels), total ERK (middle panels), and β-tubulin control (right panels).