Table 1.
Clinical characteristics of patients
| DM with RP-ILD | DM without RP-ILD | p value | |
|---|---|---|---|
| n | 9 | 10 | |
| Age, years | 69.3 ± 3.9 | 63.9 ± 14.2 | 0.68 |
| Female (n, %) | 8, 88.9 | 6, 60.0 | 0.31 |
| Disease duration (months) | 18.1 ± 39.8 | 7.6 ± 8.7 | 0.40 |
| Smokers (current and past) (%) | 11.1 | 30.0 | 0.31 |
| Number of GC pulses | 2.2 ± 1.1 | N/A | |
| PaO2/FiO2 ratio | 160 ± 90 | N/A | |
| Leukocyte count (/μL) | 9438 ± 5751 | 7620 ± 5458 | 0.35 |
| LDH (U/L) | 549 ± 357 | 376 ± 168 | 0.27 |
| KL-6 (U/mL) | 1087 ± 584 | 1419 ± 1756 | 0.46 |
| IgG (mg/dL) | 1225 ± 398 | 1452 ± 454 | 0.27 |
| Positivity for anti-CADM140/MDA5 Ab (%) | 66.7 | 50.0 | 0.76 |
| CT score (G) | 2.1 ± 0.7 | N/A | |
| CT score (F) | 1.2 ± 0.6 | N/A |
Data are mean ± SD or number of patients (percentage)
DM dermatomyositis, RP-ILD rapidly progressive-interstitial lung disease, GC glucocorticoid, PaO2/FiO2 partial arterial pressure of oxygen/fraction of inspired oxygen, KL-6 Kerbs von Lungren 6 antigen, CT computed tomograpghy, G ground glass opacity, F fibrosis