Table 2.
Characteristics of study participants
| Non-ROA n = 2120 |
ROA n = 2249 |
p Value | |
|---|---|---|---|
| Baseline characteristics | |||
| Age, years | 59.9 (9.1) | 62.7 (8.9) | < 0.001 |
| Female, n (%) | 1224 (57.7) | 1311 (58.3) | 0.71 |
| Body mass index, kg/m2 | 27.6 (4.5) | 29.8 (4.8) | < 0.001 |
| Kellgren-Lawrence grade, n (%) | – | ||
| 0 | 1432 (67.5) | – | |
| 1 | 688 (32.5) | – | |
| 2 | – | 1173 (52.2) | |
| 3 | – | 787 (35.0) | |
| 4 | – | 289 (12.8) | |
| WOMAC pain score (range 0–20) | 1.9 (2.7) | 3.7 (3.8) | < 0.001 |
| WOMAC pain score > 5, n (%) | 307 (14.5) | 760 (33.8) | < 0.001 |
| Change in knee pain and structure | |||
| Knee pain pattern over 1 year, n (%) | < 0.001 | ||
| No knee pain at both baseline and 1 year | 1669 (80.5) | 1265 (57.8) | |
| Fluctuating knee pain (pain at either baseline or 1 year) | 274 (13.2) | 464 (21.2) | |
| Persistent knee pain (pain at both baseline and 1 year) | 131 (6.3) | 459 (21.0) | |
| Annual percentage cartilage volume loss over 4 years | |||
| Medial compartment | 0.68 (1.13) | 1.36 (1.95) | < 0.001 |
| Lateral compartment | 0.73 (1.03) | 1.21 (1.41) | < 0.001 |
| Incidence of ROA over 4 years, n (%) | 165 (9.6) | – | – |
| Progression of ROA over 4 years, n (%) | – | 272 (17.8) | – |
ROA Radiographic osteoarthritis, WOMAC Western Ontario and McMaster Universities Osteoarthritis Index
Data displayed as mean (SD) or number (%)