Table 3.
Associations of baseline Western Ontario and McMaster Universities Osteoarthritis Index knee pain score with annual percentage cartilage volume loss and incidence and progression of radiographic knee osteoarthritis over 4 years
| Univariable analysis | Multivariable analysisa | |||
|---|---|---|---|---|
| Non-ROA | ||||
| Regression coefficient (95% CI) | p Value | Regression coefficient (95% CI) | p Value | |
| Annual percentage cartilage volume loss in medial compartment | 0.04 (0.01, 0.06) | 0.001 | 0.04 (0.02, 0.06) | 0.001 |
| Annual percentage cartilage volume loss in lateral compartment | 0.04 (0.02, 0.06) | < 0.001 | 0.04 (0.02, 0.06) | < 0.001 |
| OR (95% CI) | p Value | OR (95% CI) | p Value | |
| Incidence of radiographic knee osteoarthritis | 1.10 (1.05, 1.16) | < 0.001 | 1.07 (1.01, 1.13) | 0.02 |
| ROA | ||||
| Regression coefficient (95% CI) | p Value | Regression coefficient (95% CI) | p Value | |
| Annual percentage cartilage volume loss in medial compartment | 0.06 (0.03, 0.08) | < 0.001 | 0.04 (0.02, 0.07) | 0.001 |
| Annual percentage cartilage volume loss in lateral compartment | 0.06 (0.04, 0.08) | < 0.001 | 0.05 (0.03, 0.07) | < 0.001 |
| OR (95% CI) | p Value | OR (95% CI) | p Value | |
| Progression of radiographic knee osteoarthritis | 1.08 (1.05, 1.12) | < 0.001 | 1.07 (1.03, 1.10) | < 0.001 |
ROA Radiographic osteoarthritis
aAdjusted for age, gender, body mass index and Kellgren-Lawrence grade