Table 2.
Variable | Gout | Non-gout | Unadjusted | Adjusted* | ||||||
---|---|---|---|---|---|---|---|---|---|---|
n | Rate‡ | 95% CI | n | Rate‡ | 95% CI | Hazard ratio | 95% CI | Hazard ratio | 95% CI | |
Overall | 6694 | 28.6 | 27.9, 29.3 | 3953 | 15.8 | 15.3, 16.3 | 1.79 | 1.72, 1.86 | 1.78 | 1.70, 1.85 |
Male | 4608 | 23.6 | 22.9, 24.3 | 2681 | 13.0 | 12.5, 13.5 | 1.80 | 1.71, 1.89 | 1.78 | 1.69, 1.87 |
Female | 2086 | 53.8 | 51.5, 56.1 | 1272 | 28.7 | 27.1, 30.3 | 1.82 | 1.70, 1.95 | 1.79 | 1.66, 1.93 |
Age at index in years | ||||||||||
< 55 years | 690 | 5.8 | 5.4, 6.30 | 279 | 2.3 | 2.1, 2.6 | 2.52 | 2.19, 2.89 | 1.78 | 1.54, 2.07 |
55–65 | 1581 | 24.6 | 23.4, 25.8 | 844 | 12.3 | 11.5, 13.2 | 1.99 | 1.83, 2.16 | 1.76 | 1.61, 1.92 |
65–75 | 2506 | 66.2 | 63.6, 68.8 | 1498 | 33.8 | 32.1, 35.5 | 1.91 | 1.79, 2.04 | 1.87 | 1.75, 2.00 |
> 75 | 1917 | 141.0 | 134.8, 147.5 | 1332 | 78.1 | 74.0, 82.4 | 1.75 | 1.63, 1.88 | 1.71 | 1.59, 1.84 |
IMD (quintiles) | ||||||||||
1 (least deprived) | 1579 | 25.6 | 24.3, 26.9 | 914 | 13.9 | 13.0, 14.8 | 1.81 | 1.67, 1.97 | 1.84 | 1.69, 2.01 |
2 | 1689 | 29.2 | 27.9, 30.7 | 1008 | 16.2 | 15.2, 17.2 | 1.78 | 1.65, 1.92 | 1.79 | 1.65, 1.94 |
3 | 1439 | 30.9 | 29.3, 32.5 | 831 | 16.7 | 15.6, 17.9 | 1.83 | 1.68, 1.99 | 1.77 | 1.62, 1.94 |
4 | 1143 | 29.4 | 27.8, 31.2 | 698 | 16.6 | 15.4, 17.8 | 1.76 | 1.60, 1.93 | 1.78 | 1.61, 1.97 |
5 (most deprived) | 841 | 29.1 | 27.2, 31.2 | 501 | 16.5 | 15.1, 18.0 | 1.76 | 1.57, 1.96 | 1.67 | 1.49, 1.88 |
CKD chronic kidney disease, IMD index of multiple deprivation
*Adjusted for age, gender, body mass index, smoking status, diabetes mellitus, treated hypertension, rheumatoid arthritis, systemic lupus erythematosus, heart failure, IMD, myocardial infraction, cerebrovascular disease, peripheral vascular disease, history of hospitalisation, consultation rates, and non-steroidal anti-inflammatory drug exposure, when not stratified by them, ‡ per 10,000 person-years