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. 2018 Oct 30;20:243. doi: 10.1186/s13075-018-1746-1

Table 2.

Absolute rate of CKD per 10,000 person-years and hazard ratios

Variable Gout Non-gout Unadjusted Adjusted*
n Rate 95% CI n Rate 95% CI Hazard ratio 95% CI Hazard ratio 95% CI
Overall 6694 28.6 27.9, 29.3 3953 15.8 15.3, 16.3 1.79 1.72, 1.86 1.78 1.70, 1.85
Male 4608 23.6 22.9, 24.3 2681 13.0 12.5, 13.5 1.80 1.71, 1.89 1.78 1.69, 1.87
Female 2086 53.8 51.5, 56.1 1272 28.7 27.1, 30.3 1.82 1.70, 1.95 1.79 1.66, 1.93
Age at index in years
 < 55 years 690 5.8 5.4, 6.30 279 2.3 2.1, 2.6 2.52 2.19, 2.89 1.78 1.54, 2.07
 55–65 1581 24.6 23.4, 25.8 844 12.3 11.5, 13.2 1.99 1.83, 2.16 1.76 1.61, 1.92
 65–75 2506 66.2 63.6, 68.8 1498 33.8 32.1, 35.5 1.91 1.79, 2.04 1.87 1.75, 2.00
 > 75 1917 141.0 134.8, 147.5 1332 78.1 74.0, 82.4 1.75 1.63, 1.88 1.71 1.59, 1.84
IMD (quintiles)
 1 (least deprived) 1579 25.6 24.3, 26.9 914 13.9 13.0, 14.8 1.81 1.67, 1.97 1.84 1.69, 2.01
 2 1689 29.2 27.9, 30.7 1008 16.2 15.2, 17.2 1.78 1.65, 1.92 1.79 1.65, 1.94
 3 1439 30.9 29.3, 32.5 831 16.7 15.6, 17.9 1.83 1.68, 1.99 1.77 1.62, 1.94
 4 1143 29.4 27.8, 31.2 698 16.6 15.4, 17.8 1.76 1.60, 1.93 1.78 1.61, 1.97
 5 (most deprived) 841 29.1 27.2, 31.2 501 16.5 15.1, 18.0 1.76 1.57, 1.96 1.67 1.49, 1.88

CKD chronic kidney disease, IMD index of multiple deprivation

*Adjusted for age, gender, body mass index, smoking status, diabetes mellitus, treated hypertension, rheumatoid arthritis, systemic lupus erythematosus, heart failure, IMD, myocardial infraction, cerebrovascular disease, peripheral vascular disease, history of hospitalisation, consultation rates, and non-steroidal anti-inflammatory drug exposure, when not stratified by them, per 10,000 person-years