Table 1. The intervention plan and timing of the visits.
Participants | Screening (-1 week) |
FMT-day (week 0) | Visit 1 (week 1) | Visit 2 (week 3) | Visit 3 (week 12) | Visit 4 (week 20/28) |
---|---|---|---|---|---|---|
Patients | ||||||
IBS-SSS | IBS-SSS | IBS-SSS | IBS-SSS | IBS-SSS | IBS-SSS | |
IBS-SQ | IBS-SQ | IBS-SQ | ||||
History and physical examination | Bristol stool form scale | Bristol stool form scale | Bristol stool form scale | Bristol stool form scale | Bristol stool form scale | |
Blood tests | SF-NDI | SF-NDI | SF-NDI | |||
Stool tests | EPQ-N-12 | EPQ-N-12 | EPQ-N-12 | |||
HAD | HAD | HAD | ||||
Fresh stool for storage (-80°C) and analysis | Fresh stool for storage (-80°C) and analysis | Fresh stool for storage (-80°C) and analysis | Fresh stool for storage (-80°C) and analysis | Fresh stool for storage (-80°C) and analysis | ||
Gastroscopy for installation of freshly donated feces | ||||||
Donors | ||||||
History and physical examination | Fresh stool for donation | Fresh stool for storage (-80°C) and analysis | ||||
IBS-SSS | ||||||
IBS-SQ | ||||||
Blood tests | ||||||
Stool tests |
IBS-SSS: Irritable bowel syndrome-symptom severity scale; IBS-SQ: IBS symptom questionnaire; SF-NDI: short form-Nepean dyspepsia index; EPQ-N-12: The Eysenck Personality Questionnaire-Neuroticism; HAD: hospital anxiety and depression.