Table 2. Characteristics of the fecal bacterial signals between the donors at the beginning and end of the study, and patients in weeks 0, 1, 3, 12 and 20/28.
The left part of the table shows the bacterial signals given for donors and recipients at different time points before and after FMT and the directionality towards or away from that of the donors at baseline. The right part of the table shows the P-values when comparing the bacterial signals for the recipients at different time points to that for the donors at baseline.
| Bacteria strain |
Donors, Beginning of study, n = 13 |
Patients | Donors, End of study, n = 10 |
Pa Before FMT | Pb After 1 week | Pc After 3 weeks | Pd After 12 weeks | Pe After 20/28 weeks | Pf Donors | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FMT day, n = 9 | After 1 week, n = 12 | After 3 weeks, n = 9 | After 12 weeks, n = 13 | After 20/28 weeks, n = 12 | |||||||||
| Ruminococcus gnavus | 4.6±1.1 | 40±15.6 | 8±2.3 | 15.3±9 | 25±17 | 8.1±1.8 | 8.8±2 | 0.015 | >0.9 | 0.15 | 0.44 | >0.9 | 0.19 |
| Bacteroides | 27.2±4.1 | 38.9±8.3 | 47.1±16.6 | 30.9±3.7 | 55.4±12.7 | 49.3±11 | 42±5.2 | >0.9 | >0.9 | >0.9 | 0.02 | 0.1 | 0.097 |
| Bacteroides/Prevotella | 483±51.4 | 634±28.5 | 599±25.8 | 551±63.9 | 783±49.7 | 731±52 | 788±58 | 0.7 | >0.9 | >0.9 | 0.005 | 0.02 | 0.009 |
| Alistipes | 100.5±16.8 | 100.5±23 | 119±17.4 | 140±26.8 | 186±11.9 | 208±9.6 | 188±15.5 | >0.9 | >0.9 | 0.9 | 0.011 | 0.0006 | 0.03 |
| Parabacteroides | 7.6±1.8 | 7.9±2.9 | 8.3±2 | 14.6±5.4 | 11.8±1.8 | 15.7±3.5 | 19.5±3.8 | >0.9 | >0.9 | >0.9 | 0.4 | 0.3 | 0.03 |
| Actinobacteria | 287±45 | 66.6±13 | 95±23 | 197±54 | 138±29 | 92±23 | 204±57 | 0.0010 | 0.007 | 0.7 | 0.2 | 0.003 | 0.018 |
| Bifidobacteria | 324±57 | 65±13 | 97±25 | 205±57 | 150±34 | 92.5±25 | 241±72 | 0.0011 | 0.008 | 0.6 | 0.2 | 0.004 | 0.017 |
| Proteobacteria | 27±7.8 | 195±121.6 | 565±162 | 63.8±28.5 | 105±70 | 56.5±40 | 17±1.9 | >0.9 | 0.03 | >0.9 | 0.9 | >0.9 | 0.5 |
| Shigella/Escherichia | 62±23 | 260±124 | 578±128 | 116±45 | 188±77 | 90.9±65 | 41±14 | >0.9 | 0.002 | 0.8 | >0.9 | >0.9 | 0.8 |
Data are presented as the mean±SEM. Comparison: Kruskal-Wallis multiple comparisons test with Dunn’s post test
a Donors at the beginning of the study vs. patients on FMT day before fecal installation.
b Donors at the beginning of the study vs. patients 1 week after FMT.
c Donors at the beginning of the study vs. patients 3 weeks after FMT.
d Donors at the beginning of the study vs. patients 12 weeks after FMT.
e Donors at the beginning of the study vs. patients 20/28 weeks after FMT.
Paired t test
f Donors at the beginning vs. end of the study.
FMT: fecal microbiota transplantation.