Table 3. Activities of recombinant human cytochrome P450 isoforms towards compounds 1a and 2a.

	1a		2a
CYP isoform	kobs(min-1)	As % of CYP3A4	kobs(min-1)	As % of CYP3A4
CYP3A4	0.663	100	0.059	100
CYP1A2	0.009	1	<0.001	0
CYP2C9	0.050	7	<0.001	0
CYP2C19	0.071	11	0.014	24
CYP2D6	0.015	2	<0.001	0
CYP2C8	0.001	0	<0.001	0