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. 2018 Nov 9;11:7919–7934. doi: 10.2147/OTT.S180971

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© 2018 Wang et al. This work is published and licensed by Dove Medical Press Limited

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Overexpression of Bcl2L10 partially reversed the function of miR-18a on HCC cell proliferation in vitro.

Notes: (A) The Bcl2L10 plasmids promoted the mRNA and protein expression of Bcl2L10 in HCC cells (P<0.001). (B) Overexpression of Bcl2L10 partially reversed the effect of miR-18a on HCC cell proliferation (P<0.05). (C) Cell apoptosis rate was detected by flow cytometry after transfection with miR-18a mimic or miR-18a mimic + Bcl2L10 plasmids. (D) The proportion of cells in each cell cycle phase was detected using flow cytometry after cells were transfected with miR-18a mimic or miR-18a mimic + Bcl2L10 plasmids. Data were reported as mean ± SD. *P<0.05 and ***P<0.001.

Abbreviations: HCC, hepatocellular carcinoma; miR-18a, microRNA-18a; Bcl2L10, Bcl2 like 10; PI, propidium iodide.

Overexpression of Bcl2L10 partially reversed the function of miR-18a on HCC cell proliferation in vitro.

Notes: (A) The Bcl2L10 plasmids promoted the mRNA and protein expression of Bcl2L10 in HCC cells (P<0.001). (B) Overexpression of Bcl2L10 partially reversed the effect of miR-18a on HCC cell proliferation (P<0.05). (C) Cell apoptosis rate was detected by flow cytometry after transfection with miR-18a mimic or miR-18a mimic + Bcl2L10 plasmids. (D) The proportion of cells in each cell cycle phase was detected using flow cytometry after cells were transfected with miR-18a mimic or miR-18a mimic + Bcl2L10 plasmids. Data were reported as mean ± SD. *P<0.05 and ***P<0.001.

Abbreviations: HCC, hepatocellular carcinoma; miR-18a, microRNA-18a; Bcl2L10, Bcl2 like 10; PI, propidium iodide.