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. 2018 Nov 14;13(11):e0207224. doi: 10.1371/journal.pone.0207224

Table 1. Baseline characteristics.

Characteristics N = 288
Age at diagnosis, median in years (range) 51 (27–85)
Range, ages (years) n (%)
<35 years 22 (6.2)
35–39 27 (11.1)
40–49 78 (27.1)
50–59 91 (31.6)
60–69 50 (17.4)
≥70 20 (6.6)
Menopausal status n (%)
Premenopausal 174 (60.4)
Postmenopausal 114 (39.6)
Tumor size n (%)
TX 3 (1.0)
T1 7 (2.4)
T2 107 (37.1)
T3 71 (24.6)
T4 100 (34.7)
Lymph nodes n (%)
N0 64 (22.2)
N1 124 (43)
N2 86 (29.8)
N3 14 (4.8)
TNM n (%)
IIA 49 (17)
IIB 61 (21.2)
IIIA 72 (25)
IIIB 92 (32)
IIIC 14 (4.8)
Histologic subtype n (%)
Ductal 274 (95.1)
Lobular 6 (2.1)
Other 8 (2.8)
Tumor grade n (%)
G1 21 (7.3)
G2 131 (45.5)
G3 116 (40.3)
Unknown 20 (6.9)
Estrogen receptor status n (%)
Positive 178 (61.8)
Negative 110 (38.2)
Progesterone receptor status n (%)
Positive 142 (49.3)
Negative 146 (50.7)
HER 2 n (%)
Positive 103 (35.7)
Negative 184 (64)
Unknown 1 (0.3)
Biological subtype (IHC4) n (%)
Luminal A 39 (13.5)
Luminal B, HER 2- 80 (27.8)
Luminal B, HER 2+ 57 (19.8)
Her 2 enriched 46 (16)
Triple Negative 62 (21.5)
Neoadjuvant Chemotherapy regimen n (%)
Anthracycline-based only 11 (3.8)
Taxanes-based only 29 (10.1)
Anthracycline and taxane based 248 (86.1)
Pathological response n (%)
pCR 89 (30.9)
No pCR 199 (69.1)
Characteristics N = 288
Age at diagnosis, median in years (range) 51 (27–85)
Range, ages (years) n (%)
<35 years 22 (6.2)
35–39 27 (11.1)
40–49 78 (27.1)
50–59 91 (31.6)
60–69 50 (17.4)
≥70 20 (6.6)
Menopausal status n (%)
Premenopausal 174 (60.4)
Postmenopausal 114 (39.6)
Tumor size n (%)
TX 3 (1.0)
T1 7 (2.4)
T2 107 (37.1)
T3 71 (24.6)
T4 100 (34.7)
Lymph nodes n (%)
N0 64 (22.2)
N1 124 (43)
N2 86 (29.8)
N3 14 (4.8)
TNM n (%)
IIA 49 (17)
IIB 61 (21.2)
IIIA 72 (25)
IIIB 92 (32)
IIIC 14 (4.8)
Histologic subtype n (%)
Ductal 274 (95.1)
Lobular 6 (2.1)
Other 8 (2.8)
Tumor grade n (%)
G1 21 (7.3)
G2 131 (45.5)
G3 116 (40.3)
Unknown 20 (6.9)
Estrogen receptor status n (%)
Positive 178 (61.8)
Negative 110 (38.2)
Progesterone receptor status n (%)
Positive 142 (49.3)
Negative 146 (50.7)
HER 2 n (%)
Positive 103 (35.7)
Negative 184 (64)
Unknown 1 (0.3)
Biological subtype (IHC4) n (%)
Luminal A 39 (13.5)
Luminal B, HER 2- 80 (27.8)
Luminal B, HER 2+ 57 (19.8)
Her 2 enriched 46 (16)
Triple Negative 62 (21.5)
Neoadjuvant Chemotherapy regimen n (%)
Anthracycline-based only 11 (3.8)
Taxanes-based only 29 (10.1)
Anthracycline and taxane based 248 (86.1)
Pathological response n (%)
pCR 89 (30.9)
No pCR 199 (69.1)

pCR: pathological complete response