Fig. 4. Inversion and rotation enhance gene transfer to cervical DRG.

In rats that were either inverted or rotated after intrathecal AAV9 infusion, significantly more cervical DRG cells were transduced than in rats that remained upright. Nearly all transduced cells were neurons by colocalization with CaMKII (99.5%), including both small- and large-diameter DRG neurons. Scale bar, 500 μm.