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. Author manuscript; available in PMC: 2018 Nov 14.
Published in final edited form as: Circ J. 2018 Jan 19;82(4):1195–1204. doi: 10.1253/circj.CJ-17-0732

Figure 6.

Figure 6.

Effects of endothelial nitric oxide synthase (eNOS) deletion on the neuroprotective effects of Rho-associated kinase (ROCK)1 and ROCK2 deficiency. (A) Expression of ROCK1, ROCK2, eNOS, and β-actin in brain tissues of wild-type (WT), ROCK1+/− ROCK2+/−, eNOS−/−, eNOS−/−ROCK1+/−, and eNOS−/−ROCK2+/− mice. (B,C) Cerebral infarct volume (n=10–14), neurological deficit score, and (D) mortality rate following middle cerebral artery occlusion (MCAO) (n=15–19) in eNOS−/−, eNOS−/−ROCK1+/−, and eNOS−/−ROCK2+/− mice. P>0.05 for all inter-group comparisons.