TABLE 4.
Comparison of the different methods using coverage rates (in percentage) based on the top 20 genes in the aggregated list when (1) μg’s are generated from scaled t3, Exp(1), and scaled |N(0, 1)|, respectively; (2) there is no platform bias (i.e., κgp ≡ 0); and (3) a dichotomous model (DM), 5%. N(1, 1) + 95%. N(0, 1), is used to generate signal vs. non-signal genes.
MEAN | GEO | MED | Stuart | RRA | MCI | MC2 | MC3 | CEMC.k | CEMC.s | BIRRA | BARD | BiG | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
t3 | 60 | 57.6 | 58.1 | 55.5 | 45.9 | 54.5 | 60.5 | 59.1 | 56.7 | 48.3 | 13 | 54.8 | 63.3 |
Exp(1) | 71.7 | 70.8 | 70.3 | 69.6 | 62.5 | 66.7 | 73 | 71 | 66.6 | 61.9 | 16.3 | 66.2 | 75.2 |
|N (0, 1)| | 63.2 | 61.4 | 61.3 | 59.8 | 53.2 | 57.8 | 63.2 | 62.3 | 58.3 | 52.4 | 12.5 | 58.3 | 66 |
κgp = 0 | 53.1 | 51.3 | 50.8 | 48.4 | 41.6 | 46.8 | 53.5 | 52.7 | 48.4 | 40.6 | 9.6 | 48.3 | 56.2 |
DM | 38.9 | 35.6 | 36.8 | 32.6 | 25.4 | 33 | 39.8 | 40.1 | 37 | 24.1 | 6.4 | 31.6 | 37.4 |