Table 2.

Association of clinicopathological factors with pathologic complete response.

Factor	Univariate analysis			Multivariate analysis
	OR	95% CI	P value	OR	95% CI	P value
Age at diagnosis	0.97	0.94–1.00	0.09	0.98	0.94–1.02	0.34
Clinical stage III vs. II	0.79	0.33–1.91	0.60	0.73	0.24–2.20	0.57
Grade 3 vs. less than grade 3	0.99	0.47–2.10	0.98	0.97	0.37–2.52	0.94
HR+ vs. HR-	0.86	0.40–1.81	0.68	0.77	0.28–2.10	0.60
HER2 FISH ratio > 8 vs. < 8	2.06	0.84–5.06	0.11	1.47	0.50–4.33	0.48
HER2 IHC 3+ vs. less than 3+	3.56	1.37–9.24	0.01	3.71	1.13- 12.22	0.03
Pertuzumabcontaining regimen vs. not	1.72	0.73–4.02	0.21	2.75	0.85–8.88	0.09
Anthracyclinecontaining regimen vs. not	0.82	0.39–1.73	0.61	0.98	0.32–2.93	0.97

Legend: HR+, hormone receptor positive; HER2, human epidermal growth factor 2; FISH, fluorescence in situ hybridization; IHC = immunohistochemistry