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In vitro drug release profiles of formulations of twin screw granulation with different compositions of intra and extra granular binders (mean ± SD; n=6) A) F19, F20 and F21 (Compritol®888 ATO based formulations); B) F22, F23 and F24 (Precirol®ATO 5 based formulations); C) F25,F26 and F27 (Geleol™ based formulations) D) F28,F29 and F30 (formulations based on combination of lipids)
