. Author manuscript; available in PMC: 2019 Aug 30.

Published in final edited form as: Eur J Pharm Sci. 2018 May 14;121:126–138. doi: 10.1016/j.ejps.2018.05.007

Table 5.

Release kinetics of formulations of wet granulation, direct compression and twin screw granulation.

Formulation code	Zero order	First order	Higuchi	Korsmeyer- Peppas	Diffusional Exponent (n)	Hixon –Crowell Correlation coefficient (R²)
		Correlation coefficient (R²)
F1	0.9604	0.816	0.9858	0.9845	0.457	0.8566
F2	0.9586	0.8219	0.9835	0.9795	0.478	0.8786
F3	0.931	0.7731	0.9865	0.977	0.585	0.8356
F7	0.9843	0.8832	0.9926	0.9956	0.479	0.928
F8	0.8300	0.7634	0.8710	0.9573	0.681	0.7945
F9	0.9330	0.9201	0.9211	0.9954	0.535	0.9286
F13	0.9621	0.8474	0.9658	0.9641	0.669	0.8966
F14	0.9012	0.7455	0.9833	0.9395	0.939	0.8725
F15	0.9695	0.8659	0.9894	0.971	.9314	0.9438
F20	0.9873	0.8652	0.9256	0.8982	0.501	0.9819
F23	0.9569	0.8414	0.9761	0.9225	0.674	0.8899
F26	0.8816	0.7254	0.9652	0.9849	0.813	0.7864