Table 2.
Cox Proportional Hazard Models of Total Vitamin D Intake Quartiles
| Total Vitamin D Intake(IU/day) | p-value for trend | ||||
|---|---|---|---|---|---|
| <200 | [200–465) | [465, 675) | >=675 | ||
| HNC-specific Death | |||||
| # Deaths | 18 | 12 | 15 | 21 | |
| 17,592.14 p-mos | 4277.45 | 4623.77 | 4533.09 | 4157.83 | |
| HR (95% CI) † | 1.0(ref) | 0.60(0.29, 1.25) | 0.73(0.37, 1.46) | 1.01(0.54, 1.90) | .814 |
| HR (95% CI) ‡ | 1.0(ref) | 0.55(0.25, 1.20) | 0.65(0.32, 1.35) | 0.79(0.40, 1.56) | .707 |
|
| |||||
| Overall Death | |||||
| # Deaths | 27 | 24 | 25 | 32 | |
| 17,592.14 p-mos | 4277.45 | 4623.77 | 4533.09 | 4157.83 | |
| HR (95% CI) † | 1.0(ref) | 0.82(0.47, 1.42) | 0.82(0.47, 1.41) | 1.00(0.60, 1.67) | .967 |
| HR (95% CI) ‡ | 1.0(ref) | 0.71(0.39, 1.27) | 0.73(0.41, 1.29) | 0.84(0.48, 1.47) | .656 |
|
| |||||
| Recurrence | |||||
| # Recurring | 14 | 19 | 16 | 10 | |
| 13,115.27 p-mos | 3049.76 | 3509.75 | 3443.55 | 3112.21 | |
| HR (95% CI) † | 1.0(ref) | 1.16(0.58, 2.32) | 0.94(0.46, 1.93) | 0.57(0.25, 1.28) | .139 |
| HR (95% CI) ‡ | 1.0(ref) | 1.19(0.57, 2.49) | 0.90(0.42, 1.92) | 0.47(0.20, 1.10) | .048 |
age-adjusted
adjusted for age, smoking status, alcohol status, hpv status, highest education level, ACE score, total calorie intake, disease site, and stage.
N=434, Recurrence analysis N=389