Fig. 2.

Effect of p38 inhibition on EGF- and HGF-induced DNA synthesis in AsPC-1 (a) and Panc-1 (b) cells. Various doses of EGF or HGF was added to AsPC-1 (a) and Panc-1 (b) cells 30 min after adding SB203580 (10 μM) and DNA synthesis measured after 24 h of stimulation. The data represent the mean ± SEM of three independent experiments. * indicates p ≤ 0.05 and ** indicates p ≤ 0.01 (growth factor alone versus growth factor plus SB203580). # indicates p ≤ 0.05 and ## indicates p ≤ 0.01 (non-stimulated versus growth factor stimulated)