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Effect of p38 inhibition on ERK phosphorylation. Immunoblots show ERK phosphorylation induced by 10 nM EGF and 1 nM HGF in AsPC-1 (a) and Panc-1 (b) with or without SB203580 (10 μM) pretreatment. The graphs show densitometric quantification of ERK phosphorylation based on three independent experiments ± SEM. pERK was normalized to the expression of GAPDH. * indicates p ≤ 0.05 versus growth factor without SB203580
