Table 1.
Partial list of molecules differentially expressed and/or differentially phosphorylated in OKF6/TERT1-Smoke cells compared to OKF6/TERT1-Parental cells
Gene symbol | Protein Name | Protein fold change (≥2 fold) | Phosphopeptide sequence | Phosphosite | Phosphopeptide fold change (≥2 fold) |
---|---|---|---|---|---|
ICAM1 | intercellular adhesion molecule 1 | 2.6 | GTPMKPNTQAtPP | T530 | 3.3 |
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform a | 1.3 | AREGsFESR | S1248 | 4.2 |
EVPL | envoplakin | 0.9 | SAsPTVPR | S2025 | 0.5 |
TJP1 | tight junction protein ZO-1 isoform d | 0.9 | SEPSDHSRHsPQQPSNGSLR | S333 | 0.2 |
LMNA | lamin isoform A | 0.7 | LRLsPsPTSQR | S390; S392 | 0.4 |
DSG3 | desmoglein-3 | 0.5 | GsHTMLCTEDPCSR | S985 | 0.4 |
COL17A1 | collagen alpha-1(XVII) chain | 0.5 | HAYEGSSSGNssPEYPRK | S117; S118 | 0.3 |
PKP1 | plakophilin-1 isoform 1b | 0.3 | SSQSSTLSHsNR | S65 | 0.4 |
LAD1 | ladinin-1 | 0.4 | IPSKEEEADMSsPTQR | S356 | 0.4 |
KRT14 | keratin, type I cytoskeletal 14 | 0.4 | APSTYGGGLsVSSSR | S51 | 0.1 |
KRT5 | keratin, type II cytoskeletal 5 | 0.3 | sLYNLGGSK | S64 | 0.1 |
KRT16 | keratin, type I cytoskeletal 16 | 0.3 | EVFTSSsSSSSR | S448 | 0.2 |
KRT6B | keratin, type II cytoskeletal 6B | 0.4 | SGFSSIsVSR | S37 | 0.2 |
KRT6A | keratin, type II cytoskeletal 6A | 0.4 | AIGGGLSSVGGGsSTIK | S546 | 0.4 |