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. 2018 Nov 14;24(42):4738–4749. doi: 10.3748/wjg.v24.i42.4738

Table 2.

The CXC chemokines and their receptors

CXC ligand Chemokine name Receptor ELR domain
CXCL1 Growth-regulated oncogene (Gro-α) CXCR2 ELR+
CXCL2 Growth-regulated oncogene (Gro-β) CXCR2 ELR+
CXCL3 Growth-regulated oncogene (Gro-γ) CXCR2 ELR+
CXCL4 Platelet factor-4 (PF-4) CXCR3 ELR-
CXCL5 Epithelial cell-derived neutrophil-activating peptide-78 (ENA-78) CXCR2 ELR+
CXCL6 Granulocyte chemotactic protein-2 (GCP-2) CXCR1/2 ELR+
CXCL7 Neutrophil-activating peptide-2 (NAP-2) CXCR2 ELR+
CXCL8 Interleukin-8 (IL-8) CXCR1/2 ELR+
CXCL9 Monokine induced by interferon-γ (Mig) CXCR3 ELR-
CXCL10 Inducible protein-10 (IP-10) CXCR3 ELR-
CXCL11 Interferon-inducible T cell alpha chemoattractant (I-TAC) CXCR3/7 ELR-
CXCL12 Stromal cell-derived factor-1 (SDF-1) CXCR4/7 ELR-
CXCL13 B cell-attracting chemokine-1 (BCA-1) CXCR5 ELR-
CXCL16 Scavenger receptor that binds phosphatidylserine and oxidized lipoprotein (SR-PSOX) CXCR6 ELR-
CXCL17 VEGF-correlated chemokine-1 (VCC-1) CXCR8 ELR+

VEGF: Vascular endothelial growth factor.