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. 2018 Nov 14;8:16826. doi: 10.1038/s41598-018-34826-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Illustration of the CC FDs segmentation using fuzzy c-means on a chronic birdshot chorioretinopathy patient. (A) Averaged OCTA CC image; (B) elbow method to determine appropriate number of clusters; membership is designated to each cluster of signals; (C) fuzzy c-means membership map of original CC image, all pixels were assigned into 5 different memberships based on fuzzy logic; (D) binary CC FD map, pixels presented in black represent identified CC FDs.