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. 2018 Nov 14;8:16826. doi: 10.1038/s41598-018-34826-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Visual illustration of CC FDs detection with averaging for the scans obtained from equatorial region. (Panel A) Macular CC OCTA images with single scan, three scans averaged, and five scans averaged, respectively. (Panel B) Macular CC vasculature segmented by fuzzy c-means algorithm with single scan, three scans averaged, and five scans averaged, respectively. (Panel C) Segmented macular CC FD with single scan, three scans averaged, and five scans averaged, respectively.