Table 2.
Genetic correlations across life history speed indicators (four reproductive traits and three longevity traits) and broad antisocial behaviour
| Phenotype | Sample size | SNP h2 | rg (s.e.) | Bivariate intercept | P-value |
|---|---|---|---|---|---|
| Age at menarche | 182.416 | 0.21 | 0.026 (0.085) | −0.0083 | 0.76 |
| Age at first birth | 222.037 | 0.063 | −0.64 (0.19) | −0.0003 | 0.0008** |
| Number of children ever born | 318.863 | 0.025 | 0.50 (0.18) | −0.007 | 0.0065** |
| Age at menopause | 69.360 | 0.13 | −0.10 (0.144) | −0.0016 | 0.48 |
| Mother's age at death | 52.776 | 0.040 | −0.51 (0.26) | −0.0017 | 0.045* |
| Father's age at death | 63.775 | 0.042 | −0.52 (0.24) | −0.0036 | 0.026* |
| Parents’ age at death | 45.627 | 0.032 | −0.70 (0.29) | 0.0093 | 0.015* |
Genome-wide association study summary statistics from our combined analyses were used to calculate the rg values with other traits. Single nucleotide polymorphism (SNP) h2 is the estimation of narrow-sense heritability contributed by common SNPs. rg is the genetic correlation and is calculated with the LDSC software package, using pre-calculated linkage disequilibrium scores from Bulik-Sullivan et al.8
*
Nominally significant (P < 0.05), ** Significant at the multiple-testing corrected P-value (0.0071).