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. 2018 Sep 5;2(6):406–412. doi: 10.1002/ags3.12202

Table 1.

Recent RCTs and meta‐analyses comparing outcomes of robotic versus laparoscopic or open surgery for rectal cancer

First author Year Study design Number of Patients CRM involvement Conversion rate
RALS CLS Result P value Difference Result P value Difference
RALS vs CLS
Jayne 2017 RCT 237 234 Odds ratio 0.78 N.S. No difference Odds ratio 0.61 N.S. No Difference
Prete 2017 Meta‐analysis 334 337 Risk ratio 0.82 N.S. No difference Risk ratio 0.58 0.04 Lower in RALS
Li 2017 Meta‐analysis 1726 1875 Odds ratio 0.80 N.S. No difference Odds ratio 0.35 <0.01 Lower in RALS
Cui 2017 Meta‐analysis 473 476 Risk difference −0.02 N.S. No difference Risk difference −0.05 0.02 Lower in RALS
Sun 2016 Meta‐analysis 324 268 Odds ratio 0.50 0.05 Lower in RALS Odds ratio 0.07 <0.01 Lower in RALS
Xiong 2015 Meta‐analysis 554 675 Odds ratio 0.44 0.04 Lower in RALS Odds ratio 0.23 <0.01 Lower in RALS
RALS vs OS RALS OS
Liao 2016 Meta‐analysis 498 576 Mean difference −0.22 N.S. No Difference Not Stated
Operative time Length of hospital stay Complication
Result (min) P‐value Difference Result (d) P‐value Difference Result P value Difference
Mean difference 37.5 Not stated Longer in RALS Mean difference −0.2 N.S. No difference Odds ratio 1.04 N.S. No difference
Mean difference 38.43 <0.01 Longer in RALS Mean difference −0.61 N.S. No difference RALS 27.3%, CLS 26.7% N.S. No difference
Weighted mean difference 57.43 <0.01 Longer in RALS Weighted mean difference −0.69 N.S. No difference Odds ratio 1.02 N.S. No difference
Mean difference 33.73 <0.01 Longer in RALS Mean difference −1.07 <0.01 Shorter in RALS Odds ratio 0.58 <0.01 Lower in RALS
Mean difference 28.4 N.S. No Difference Mean difference −1.03 <0.01 Shorter in RALS Mean difference 0.65 0.04 Lower in RALS
Weighted mean difference 17.34 N.S. No Difference Weighted mean difference −0.37 N.S. No difference Odds ratio 0.95 N.S. No difference
Mean difference 55.76 <0.01 longer in RALS Mean difference −2.10 <0.01 Shorter in RALS Odds ratio 1.00 N.S. No difference

CLS, conventional laparoscopic surgery; N.S., not significant; RALS, robotic‐assisted laparoscopic surgery; RCT, randomized control trial.