Table 6A: First Generation iStent - Efficacy Outcomes of Phaco-iStent versus iStent Implantation Alone

		Phaco-istent						Istent implantation alone						Meta-analysis
Outcome		Mean		Standard deviation		Number of eyes		Mean		Standard deviation		Number of eyes		Weighted mean difference		95% CI –Lower bound		95% CI –Upper bound		P-value
IOP reduction Preoperative		4.20		1.82		1123		11.64		2.47		173		–7.44		–7.82		–7.06		p <0.001
IOP Postoperative		19.27		2.78		1076		24.99		0.88		173		–5.72		–5.93		–5.51		p <0.001
IOP Reduction in		14.64		1.21		959		13.22		1.72		173		1.42		1.15		1.69		p <0.001
medications		0.99		0.49		1123		1.33		0.46		173		–0.34		–0.41		–0.27		p <0.001
Preoperative medications		1.62		0.60		1172		1.87		0.44		173		–0.25		–0.32		–0.18		p <0.001
Postoperative medications		0.73		0.36		1172		0.55		0.87		173		0.18		0.05		0.31		p = 0.007

*IOP = Intraocular pressure. CI = Confidence interval. Note: Red text denotes endpoints that substantially differed from those of the original analysis.