Table 1. Baseline clinical characteristics of all participants.
| Variable | CTEPH without OSA (n=25) | CTEPH with OSA (n=32) | P value |
|---|---|---|---|
| Clinical parameters | |||
| Age (years) | 50±12 | 57±9 | 0.020 |
| Males/females | 10/15 | 21/11 | 0.054 |
| BMI (kg·m−2) | 23.32±2.95 | 24.98±3.06 | 0.044 |
| Smoking | 6 | 14 | 0.121 |
| 6-MWD (m) | 395.52±91.86 | 373.67±76.28 | 0.363 |
| WHO FC I–II/III–IV | 14/11 | 9/23 | 0.033 |
| PE or VTE history | 13 | 21 | 0.176 |
| Comorbidities | |||
| Coronary heart disease | 1 | 3 | 0.431 |
| Diabetes mellitus | 3 | 5 | 0.696 |
| Systemic hypertension | 4 | 10 | 0.184 |
| Dyslipidemia | 3 | 9 | 0.138 |
| Drug therapy | |||
| Targeting medication (none/single/combination) | 6/15/4 | 9/17/6 | 0.874 |
| Positive inotropes | 19 | 19 | 0.186 |
| Diuretics | 24 | 29 | 0.431 |
Continuous variables are presented as mean ± SD. Categorical variables are given as counts. CTEPH, chronic thromboembolic pulmonary hypertension; OSA, obstructive sleep apnea; WHO FC, World Health Organization functional class; BMI, body mass index; 6-MWD, six minutes walking distance.