Table 3. Parameters including pulmonary function, arterial blood gas and sleep study of all participants.
| Variable | CTEPH without OSA (n=25) | CTEPH with OSA (n=32) | P value |
|---|---|---|---|
| Pulmonary function (% pred) | |||
| FEV1 | 76.95±13.09 | 73.92 ±14.55 | 0.671 |
| FVC | 84.00±11.07 | 84.38±16.06 | 0.786 |
| FEV1/FVC | 95.81±8.61 | 92.50±9.14 | 0.431 |
| TLC | 81.67±7.78 | 79.38±13.05 | 0.618 |
| DLCO | 68.57±14.54 | 67.96±9.46 | 0.943 |
| Arterial blood gas | |||
| PaO2 (mmHg) | 68.22±13.27 | 60.13±13.48 | 0.008 |
| PaCO2 (mmHg) | 36.78±5.27 | 34.45±4.79 | 0.104 |
| SPO2 (%) | 93.26±2.25 | 90.32±4.16 | 0.004 |
| Sleep study | |||
| AHI | 2.43 (0.85–4.20) | 16.74 (7.65–23.65) | <0.001 |
| ODI | 3.50 (1.75–6.05) | 13.35 (8.40–31.45) | <0.001 |
| SPO2-min (%) | 80.28±8.75 | 77.25±7.82 | 0.041 |
| SPO2 <90% (%) | 43.15±33.08 | 49.20±32.88 | 0.495 |
Data are presented as mean ± SD or median (interquartile range). CTEPH, chronic thromboembolic pulmonary hypertension; OSA, obstructive sleep apnea; FEV1, forced expiratory volume at first second; FVC, forced vital capacity; TLC, total lung capacity; DLCO, diffusion capacity for carbon monoxide of the lung; PaO2, partial pressure of oxygen; PaCO2, partial pressure of carbon dioxide; SPO2, oxygen saturation; AHI, apnea-hypopnea index; ODI, oxygen desaturation index; SPO2-min, minimum oxygen saturation; SPO2 <90%, time spent lower than 90% of oxygen saturation.