Table 2. Clinical characteristics of obesity hypoventilation syndrome patients with AHI <30/hr with and without left ventricle diastolic dysfunction (LVDD).
| Variable total (n=38) | Mean ± SD/n (%)/median (25th–75th percentile) | P value | |
|---|---|---|---|
| No LVDD (n=11) | With LVDD (n=27) | ||
| Gender (male) | 2 (18.2) | 7 (25.9) | 1.000 |
| Age (years) | 55±17.8 | 57.6±13.5 | 0.632 |
| BMI (kg/m2) | 41.5±4.5 | 47.4±6.5 | 0.009 |
| PaCO2 (mmHg) | 56.4±11.4 | 57.3±11.1 | 0.831 |
| PaO2 (mmHg) | 61.7±11.9 | 61.4±13.1 | 0.937 |
| FVC (% predicted) | 41.8±17.8 | 48.1±19.4 | 0.481 |
| FEV1 (% predicted) | 43±15.5 | 46.9±16.6 | 0.620 |
| AHI (events/hr) | 12.3±8.5 | 13.9±8.7 | 0.622 |
| AHI-NREM (events/hr) | 11±8.6 | 11±8.5 | 0.998 |
| AHI-REM (events/hr) | 19.7±18.2 | 31.1±27.5 | 0.253 |
| Sleep latency (mins) | 14 (7–36.9) | 10.8 (6–51.9) | 0.747 |
| WASO (mins) | 82.3±83.5 | 34.5 (8.8–84.3) | 0.218 |
| Desaturation index (desaturations/hr) | 6 (2.0–41.0) | 12 (5.3–27.1) | 0.525 |
| Arousal index (arousals/hr) | 21.2±10.3 | 23.9±12.5 | 0.541 |
| Time with SpO2 <90% (mins) | 47.7±39 | 75.5 (1–99.2) | 0.769 |
| Time with SpO2 <95% (mins) | 67.8±37.6 | 99.5 (42.8–100) | 0.373 |
| Hypertension (%) | 6 (54.5) | 24 (89.0) | 0.031 |
| Diabetes (%) | 6 (54.5) | 18 (67.0) | 0.263 |
| Ischemic heart disease (%) | 1 (9.1) | 3 (11.1) | 1.000 |
| Chronic kidney disease (%) | 1 (9.1) | 1 (3.7) | 0.524 |
| Hypothyroidism (%) | 4 (36.4) | 1 (3.7) | 0.023 |
PaCO2, partial pressure carbon dioxide; PaO2, partial pressure oxygen; FVC, forced vital capacity; FEV1, forced expiratory volume in first second; BMI, body mass index; AHI, apnea hypopnea index; REM, rapid eye movement; NREM, non-rapid eye, movement; WASO, wakefulness after sleep onset; SpO2, blood oxygen saturation; SD, standard deviation.