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. 2018 Oct 24;18(6):5445–5454. doi: 10.3892/mmr.2018.9586

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Copyright: © Su et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Changes in renal function and histopathology in rats from each group. Levels of (A) serum creatinine and (B) BUN were measured via blood biochemistry. (C) Representative images of pathological alterations in the kidney tissues of rats (H&E staining; ×200 magnification). (D) Degrees of renal tubulointerstitial injury were evaluated using pathological scoring criteria. The results are presented as the mean ± standard deviation. n=10/group. *P<0.05 CIR vs. CON; ^#P<0.05 RAPA vs. CIR. CON, control group; CIR, cerebral ischemia-reperfusion; RAPA, rapamycin pre-treatment prior to CIR; BUN, blood urea nitrogen; H&E, hematoxylin and eosin.