Figure 2.

Establishment of mouse chronic unpredictable mild stress model and inhibition of depression by SLPN. (a) Body weights variation in CUMS mice and the reverse effect of SLPN. (b) Immobility time in FST of CUMS mice and the reverse effect of SLPN. (c) Immobility time in TST of CUMS mice and the reverse effect of SLPN. CUMS: chronic unpredictable mild stresse; FST: forced swimming test; SLPN: Total saponins from the leaves of Panax notoginseng; NC: negative control; TST: tail suspension test; ** and ***, v.s. NC, refer to a p value of <0.01 and <0.001 respectively. ⁺⁺ and ⁺⁺⁺, v.s. CUMS, refer to a p value of <0.01 and <0.001 respectively