Table 6.

Regions where increasing alcohol exposure is associated with smaller activation increases in boys during the invisible condition compared to the visible condition (p < 0.05, cluster‐size corrected, all clusters > 1,026 voxels). Coordinates are Talairach coordinates of the peak voxel

Lobe	Region	BA	x	y	z	No. of voxelsa	r or ßb (p)
Temporal	Right transverse temporal gyrus extending to superior temporal gyrus and insula	13, 41, 42	47	−26	12	1,041	−0.72 (0.001)
Frontal	Right precentral gyrus extending to inferior frontal gyrus, insula, and middle frontal gyrus	6, 9, 13, 44	32	−5	29	2,182	−0.71 (0.001)
Basal ganglia	Bilateral caudate extending to thalamus and lentiform nucleus	‐	−10	−2	15	2,247	−0.71 (0.001)
Frontalc	Right middle frontal gyrus extending to claustrum, insula, and inferior frontal gyrus	13, 46	38	28	18	1,082	−0.65 (0.002)
Limbic	Right parahippocampal gyrus extending to lentiform nucleus and claustrum	‐	23	−2	−9	1888	−0.71 (0.001)
Parietal	Bilateral precuneus extending to left posterior cingulate	7, 31	8	−53	45	2,100	−0.63 (0.004)

AA: absolute alcohol; BA: Brodmann area; first region mentioned = region at the peak voxel; other regions arranged in order of decreasing size.

^aVoxel size refers to the 1 × 1 × 1 mm³ resolution of the iso‐voxeled structural images.

^bPearson correlation or standardized regression coefficient (when adjusting for potential confounding) of mean % signal change in the cluster with AA/day.

^cAdjusted for age at testing.