Table 3.
Measures of diagnostic performance for the evaluated MRI signs in Multiple Sclerosis and Fabry disease patients
| Corpus callosum involvement | Infratentorial involvement | Corpus callosum + Infratentorial involvement | Involvement in at least one area | |
|---|---|---|---|---|
| Sensitivity (%) | 89 | 87 | 82 | 94 |
| Specificity (%) | 94 | 88 | 97 | 85 |
| Positive predictive value (%) | 94 | 87 | 96 | 86 |
| Negative predictive value (%) | 90 | 88 | 85 | 93 |
| Accuracy (%) | 92 | 88 | 90 | 90 |
| Positive likelihood ratio | 14.8 | 7.2 | 27.3 | 6.3 |
| Negative likelihood ratio | 0.12 | 0.15 | 0.18 | 0.07 |
| Diagnostic odds ratio | 137.1 | 52.3 | 163.3 | 93.7 |