Table I.

Gene Ontology term enrichment analysis of the differentially expressed genes (top 10 terms selected according to P-value).

A, Biological process
Term	Description	Count	P-value
GO:0051301	Cell division	96	1.40×10−26
GO:0007067	Mitotic nuclear division	70	2.80×10−20
GO:0006260	DNA replication	52	9.60×10−19
GO:0007062	Sister chromatid cohesion	37	1.69×10−14
GO:0006270	DNA replication initiation	18	5.43×10−11
GO:0000082	G1/S transition of mitotic cell cycle	32	7.00×10−11
GO:0000722	Telomere maintenance via recombination	16	7.09×10−9
GO:0000731	DNA synthesis involved in DNA repair	15	2.63×10−7
GO:0007059	Chromosome segregation	21	2.99×10−7
GO:0000086	G2/M transition of mitotic cell cycle	31	5.38×10−7
B, Cellular component
Term	Description	Count	P-value
GO:0005654	Nucleoplasm	354	2.06×10−21
GO:0005634	Nucleus	565	6.15×10−15
GO:0005737	Cytoplasm	523	2.26×10−10
GO:0000777	Condensed chromosome kinetochore	26	9.69×10−9
GO:0000775	Chromosome, centromeric region	20	4.06×10−8
GO:0005829	Cytosol	343	5.61×10−8
GO:0000776	Kinetochore	23	2.22×10−7
GO:0030496	Midbody	30	2.56×10−7
GO:0005813	Centrosome	65	6.05×10−7
GO:0005819	Spindle	26	8.38×10−6
C, Molecular function
Term	Description	Count	P-value
GO:0005515	Protein binding	842	2.67×10−11
GO:0019901	Protein kinase binding	60	1.10×10−6
GO:0003677	DNA binding	180	1.19×10−4
GO:0005524	ATP binding	163	1.33×10−4
GO:0004674	Protein serine/threonine kinase activity	50	9.04×10−4
GO:0004842	Ubiquitin-protein transferase activity	45	9.53×10−4
GO:0003697	Single-stranded DNA binding	18	0.001422
GO:0016874	Ligase activity	38	0.001512
GO:0043130	Ubiquitin binding	16	0.00157
GO:0042802	Identical protein binding	85	0.002182

ATP, adenosine triphosphate.