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. 2018 Oct 4;18(6):5058–5068. doi: 10.3892/mmr.2018.9534

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Validation of microarray results by RT-qPCR and analysis of SOX2OT function by GO enrichment. (A) Certain mRNAs and highly conserved long noncoding RNAs according to UCSC were chosen for RT-qPCR validation. Results demonstrated consistency between these two methods except for Gm15217 and Pvt1. (B) All the SOX2OT-associated mRNAs were analyzed in GO enrichment. Glutathione metabolic, oxidoreductase activity, flavonoid metabolic and lipid metabolic processes are enriched. RT-qPCR, reverse transcription quantitative polymerase chain reaction; GO, gene ontology; DN, diabetic nephropathy; SOX2OT, SOX2 original transcript.