Table I.

Data of mice at the end point of the experiment.

Parameter	Control (n=3)	DN (n=3)	P-value
Body weight (g)	23.27±0.30	39.20±0.35	<0.0001
Fasting blood glucose (mmol/l)	7.367±0.26	30.33±1.44	<0.0001
Urinary protein/creatinine ratio (g/g)	1.477±0.12	13.32±1.80	0.0028
Serum creatinine (µmol/l)	33.30±3.30	41.47±1.38	0.0842
Blood urea nitrogen (mmol/l)	8.627±0.47	13.38±0.25	0.0009

Control, nondiabetic db/m mice; DN, diabetic db/db mice. P<0.05 is considered as statistically different between two groups. Values are presented as the mean ± standard deviation.