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Effect of UVB irradiation on HSF2. (A) UVB irradiation reduces the proliferation of HSF2 cells in a time- and dose-dependent manner. (B) UVB irradiation decreased the concentrations of COL-I and COL-III, and increased the concentrations of MMP1 and MMP3 in HSF2 cells. (C) UVB irradiation dose-dependently upregulated the protein level of p-P38. *P<0.05, **P<0.01 compared with 0 mJ/cm2 (n=3). UVB, ultraviolet radiation B; HSF2, human skin fibroblasts.
