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. 2018 Oct 25;18(6):5473–5480. doi: 10.3892/mmr.2018.9594

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Copyright: © Fan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Effect of klotho overexpressed ADSCs on co-cultured HSF2 under UVB irradiation. (A) Relative mRNA expressions of MMP1 and MMP3 in HSF2 cells. (B) Proteins level of COL-I, COL-III, MMP1, MMP3, p-P38 and P38 in HSF2 cells. NC, HSF2 cells separated from HSF2 + ADSCs group; EPC, HSF2 cells separated from HSF2 + ADSCs + empty plasmid control group; OE, HSF2 cells separated from HSF2 + ADSCs + klotho OE group. *P<0.05, **P<0.01 compared with EPC (n=3). OE, overexpression; ADSCs, adipose-derived stem cells; HSF2, human skin fibroblasts; EPC, empty plasmid control group.