Figure 5.

Alterations in E-cadherin and vimentin expression in FAK siRNA-treated cells. (A) E-cadherin (green) and vimentin (red) were co-stained in cells transfected with FAK siRNA or the negative control siRNA. E-cadherin and vimentin are markers of epithelial cells and mesenchymal cells, respectively. Nuclei were counterstained with DAPI (blue). Magnification, ×400. (B) Percentage of vimentin positive cells in endometrial cells following transfection with either FAK siRNA or negative control siRNA. The positive expression of vimentin reflected the degree of EMT in the FAK siRNA and negative control groups. *P<0.05 vs. negative control. FAK, focal adhesion kinase; siRNA, small interfering RNA.