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. 2018 Sep 20;18(6):4931–4939. doi: 10.3892/mmr.2018.9495

Figure 2.

Figure 2.

Mini-gene system encoding wild-type and mutant c.1458T>C. The nucleotide sequence of the exon 12 with wild-type and mutant APC∆486s, together with 264 bp of flanking intron 12, carrying the XhoI restriction site, and 210 bp of flanking intron 13, carrying the HindIII restriction site. APC, adenomatous polyposis coli; bp, base pairs; IVS, intervening sequence.