Table II.
Association between SPRY4 expression and clinicopathological characteristics in breast cancer.
| Variables | Total n (n=78) | Low expression (n=40) | High expression (n=38) | P-value |
|---|---|---|---|---|
| Age, years | 0.820 | |||
| ≤50 | 35 | 17 | 18 | |
| >50 | 43 | 23 | 20 | |
| Tumor size | 0.361 | |||
| T1-T2 | 44 | 25 | 19 | |
| T3-T4 | 34 | 15 | 19 | |
| Grade | 0.815 | |||
| Well and moderately | 49 | 26 | 23 | |
| Poor | 29 | 14 | 15 | |
| Lymph node metastasis | 0.038a | |||
| Present | 58 | 34 | 24 | |
| Absent | 20 | 6 | 14 | |
| Distant metastasis | 0.029a | |||
| Present | 9 | 8 | 1 | |
| Absent | 69 | 32 | 37 | |
| TNM stage | 0.035a | |||
| I–II | 50 | 21 | 29 | |
| III–IV | 28 | 19 | 9 |
a
P<0.05. TNM, tumor, node, metastasis.