Table II.
Patient characteristics according to the immunohistochemical expression of CYP4F2 in hepatocellular carcinoma (n=113).
| CYP4F2 expression | ||||
|---|---|---|---|---|
| Characteristics | Total n (%) | Low (%) [80 (100.0)] | High (%) [33 (100.0)] | P-value |
| Age (years) | 113 (100.0) | 57.53±9.467 | 59.48±10.028 | 0.376 |
| Gender | 0.932 | |||
| Male | 85 (75.2) | 60 (75.0) | 25 (75.8) | |
| Female | 28 (24.8) | 20 (25.0) | 8 (24.2) | |
| HBV or HCV | 0.241 | |||
| Negative | 23 (20.4) | 14 (17.5) | 9 (27.3) | |
| Positive | 90 (79.6) | 66 (82.5) | 24 (72.7) | |
| Liver cirrhosis | 0.932 | |||
| Negative | 28 (24.8) | 20 (25.0) | 8 (24.2) | |
| Positive | 85 (75.2) | 60 (75.0) | 25 (75.8) | |
| Histologic grade | 0.321a | |||
| 1 (well) | 16 (14.2) | 12 (15.0) | 4 (12.1) | |
| 2 (moderate) | 76 (67.3) | 55 (68.8) | 21 (63.6) | |
| 3 (poorly) | 21 (18.6) | 13 (16.3) | 8 (24.2) | |
| 4 (undifferentiated) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| Pathologic stage | 0.022b | |||
| I | 31 (27.4) | 17 (21.3) | 14 (42.4) | |
| II | 70 (61.9) | 51 (63.8) | 19 (57.6) | |
| III | 11 (9.7) | 11 (13.8) | 0 (0.0) | |
| IV | 1 (0.9) | 1 (1.3) | 0 (0.0) | |
a
Grade 1/2 vs. Grade 3/4
b
Stage I vs. Stage II–IV. HBV, hepatitis B viral infection; HCV, hepatitis C viral infection' CYP4F2, cytochrome P450 family 4 member 2.